racing-resize-638x300

CAR T IMMUNOTHERAPY REVS UP FOR GLIOBLASTOMA

A NEW CLINICAL TRIAL IN GLIOBLASTOMA HAS BEEN LAUNCHED BASED ON AN INNOVATIVE IMMUNOTHERAPEUTIC TECHNIQUE – THE CAR T CELL WHICH CAN MODIFY THEN HARNESS A PATIENT’S OWN T CELLS TO FIGHT THEIR DISEASE. Immunotherapy news (including our blog) often focusses on checkpoint inhibitors likeanti-PD-1 and anti-CTLA-4 antibodies, as they make important leaps forward in… Read more »

metamorphosis-resize-638x300

PRECISION PROFILING USING PDX MODELS: THE EASY WAY TO TRANSFORM YOUR DRUG DISCOVERY PROGRAM

IMPROVED PRECLINICAL MODELS ARE NEEDED IN ONCOLOGY DRUG DEVELOPMENT TO REDUCE THE HIGH FAILURE RATE OF NEW AGENTS. PRECISION PROFILING TRANSLATIONAL PLATFORMS ARE PROVIDING THESE TOOLS, USING PATIENT-DERIVED XENOGRAFT MODELS TO REFLECT THE DIVERSITY OF THE HUMAN CANCER PATIENT POPULATION. CROWN BIOSCIENCE ARE CURRENTLY EXPANDING OUR DIVERSITY AND PDX COLLECTION THROUGH THE EXCITING ACQUISITION OF… Read more »

breakthrough-face-resize-638x300

BLADDER CANCER BREAKTHROUGH FOR IMMUNOTHERAP

NEW TREATMENTS FOR BLADDER CANCER HAVE BEEN EXTREMELY SCARCE OVER THE PAST DECADES. HOWEVER, THE CONTINUED RISE OF CHECKPOINT INHIBITOR IMMUNOTHERAPIES MAY BE PROVIDING A NEW BREAKTHROUGH FOR METASTATIC DISEASE. NEW DEVELOPMENTS IN THE NEXT GENERATION OF IMMUNO-ONCOLOGY MODELS ARE ALSO UP AND COMING THANKS TO AN EXTENDED ALLIANCE BETWEEN CROWN BIOSCIENCE AND THE NATIONAL… Read more »